Estimation Of Levodopa Concentration In The Treatment Of Parkinson’s Disease

Abstract

Parkinson's disease is currently treated with drugs as a primary treatment. Common drugs used to treat the disease are levodopa and carbodipopa. Levodopa is a substrate of the neurotransmitter called dopamine. Levodopa has a mechanism for increasing dopamine levels in the brain, which is the mechanism of dopamine neurotransmitters in the brain. Carbidopa prevents levodopa from decomposing in the blood. The delivery of drugs is done in three ways, intravenous, oral and nasal. Calculation of levodopa concentrations in the blood, peripheral, and brain of drug administration using the combination of numerical methods and computer programs. The graph of the relationship between the concentration of levodopa and the time in each form of drug administration is compared