Central nervous system endothelial hyperplasia, a treatable multiple choking dementia

Abstract

Neoplastic endothelial hyperplasia is a rare vascular disease characterized by a series of bizarre neurological symptoms such as dementia, stroke-like attacks, and skin lesions. There is extensive vascular endothelial cell proliferation in blood vessels throughout the body. It is also called "systemic proliferative endothelial hyperplasia" and "diffuse malignant endothelial hyperplasia" in the literature. This article reports one such case with a significant response to steroid treatment of neurological symptoms. Case Report: A 59-year-old right-handed woman was admitted to the hospital with progressive dementia and left hemiparesis. Two months ago, he suddenly suffered from aphasia and weakness in the right half of his body. A week later, he had a brain scan at a local hospital due to multiple episodes of incoherent speech.