The efficacy of different treatment strategies for aneurysmal oculomotor nerve palsy

Abstract

Objective To investigate the effects of microsurgical aneurysm clipping and endovascular interventional embolization on the curative effect of aneurysmal oculomotor nerve palsy (OMNP). Methods The clinical data and follow-up results of 25 patients with intracranial aneurysm complicated with OMNP admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2018 to October 2020 were analyzed, and microsurgical aneurysm clipping and endovascular interventional embolization were compared. Postoperative recovery of oculomotor nerve function in patients with different degrees of OMNP before and after surgery. Results The patients in this group were hospitalized for an average of (9.72±3.82) days after operation. Three cases (12.0%) of OMNP completely recovered, 10 cases (40.0%) partially recovered, and 12 cases (48.0%) did not recover. There was no exacerbation of OMNP symptoms. At the follow-up of 6 months after surgery, 6/25 cases (24.0%) of OMNP symptoms had completely recovered, including 2/10 cases (20%) in the embolization group and 4/14 cases (28.6%) in the clipping group; 10/25 cases had partial recovery. (40.0%), including 5/10 cases (50%) in the embolization group and 5/14 cases (35.7%) in the clipping group; 9/25 cases (36.0%) did not recover, including 3/10 cases (30%) in the embolization group ), clipping group 5 cases/14 (35.7%). Conclusion Both microsurgical aneurysm clipping and endovascular interventional embolization can improve aneurysmal OMNP. [International Journal of Neurology Neurosurgery, 2021, 48(6):526-529.]