Sensitvity of core needle biopsy in soft tissue and bone tumors at clear mediradiant hospital, Mysore

Abstract

Background and objectives:

The objectives of the study is assessment of  sensitivity and specificity of core needle biopsy in soft tissue and bone tumors, to study the complications arising after core needle biopsy, and  study the limitations of core needle biopsy in soft tissue and bone tumors.

Methods:

During the period from November 2015 to April 2017, 79 patients with soft tissue and bone tumors underwent core needle biopsy and  surgery after giving their consent at our institute. The comparison of  core needle biopsy result was done with the final histopathology report after definitive surgery and sensitivity and specificity was determined.

Results:

A total of 79 patients (47 patients with soft tissue tumors and 32 patients with bone tumors) underwent core needle biopsy followed by definitive surgery in this study. The comparison of core needle biopsy report was done with the final histopathology report. Among 47 cases of soft tissue tumors, which were analysed for diagnostic accuracy, accuracy rate was 91.49%. 80.85 % had a true positive result, 4.25% had a true negative, and 4.25% had false negative report. The sensitivity and specificity of CNB in the series was 91.11% and 100% respectively. The negative predictive value was 33.33% with positive predictive value of 100%. tissue tumors.

Among 32 patients with bone tumors, which were analysed for diagnostic accuracy, accuracy rate was 96.88%, amongst which 81.25 % had a true positive result, 6.25% had a true negative, 3.12% had false positive and 9.38% had false negative report. The sensitivity and specificity of CNB in the series was 92.85% and 75% respectively. The negative predictive value was 60% with positive predictive value of 96.29%.Among 79 patients with soft tissue and bone tumors which were analysed for diagnostic accuracy, accuracy rate was 92.11%, amongst which 81.01 % had a true positive result, 5.06% had a true negative, 1.26% had false positive and 8.86% had false negative report. The sensitivity and specificity of CNB in the series was 90.14% and 80% respectively. The negative predictive value was 36.36% with positive predictive value of 98.46%.