Consanguinity Remains A Challenge: A Case Study And Algorithm On Malignant Osteopetrosis In A Paediatric Patient

Abstract

Osteopetrosis is a class of rare hereditary skeletal illnesses characterised by a substantial rise in bone density brought by a decrease in normal osteoclast activity. A ten percentile of patients with osteopetrosis go on to develop osteomyelitis, which typically affects the mandible. Treatment of osteopetrosis stays complicated and often unsatisfactory. A 7-year-old male child reported with draining sinus wrt left mandibular arch. The child had associated cardinal general features of suspected osteopetrosis with suppurative osteomyelitis of mandible.

This case report highlighted logarithm and unnoticed case of osteopetrosis born to consanguinous couple.