Systematic examination of neurological problems such as Guillain-Barré and myasthenia gravis in children and adults involved in infection with the help of radiological and pharmaceutical techniques

Authors

  • Tina Nabatchi Ahmadi, Moein Jahanian, Farzaneh Ahmadi Mirghaed, Sannar Sattar Albuzyad, Farzad Mahshad* Author

Keywords:

Guillain-Barré, myasthenia gravis, infection, radiology and drug techniques, nerve signal.

Abstract

In the present study, a systematic investigation of neurological problems such as Guillain-Barré and myasthenia gravis in children and adults involved in infection with the help of radiological and pharmaceutical techniques has been done. This disease is in the category of autoimmune diseases, which is associated with acute nerve and muscle failure. The results of the present study show that among the first and most obvious signs and symptoms of Guillain-Barre syndrome are the tingling in the legs and the presence of weakness in them. In acute cases, these problems gradually cause paralysis of the whole body. These symptoms can have an upward trend for 2 to 4 weeks. Myasthenia gravis, whose name is composed of two words, myasthenia, which means muscle weakness, and gravis, which means heavy or severe, is an autoimmune disorder in which the body's defense system attacks its own tissues and causes muscle weakness of varying degrees in people. and it is difficult to recognize. The results of the present study indicate that in myasthenia gravis, the immune system produces antibodies that block and destroy many of the neurotransmitter receptor sites called acetylcholine. By reducing the number of available receptor sites, the muscles receive fewer nerve signals, resulting in weakness. Antibodies also block the action of a protein called tyrosine kinase, which is a muscle-specific receptor. This protein plays a role in the formation of the neuromuscular junction. Antibodies that disrupt this protein can lead to myasthenia gravis.

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Published

2024-05-23

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Section

Articles