Dynamic changes in local cerebral blood flow, pressure, cerebrospinal fluid pH and lactate system in the acute phase of craniocerebral injury

Abstract

The author reports the study of 23 cases of severe craniocerebral injury in the acute phase. All patients were in a state of deep coma when they were admitted to hospital. Imaging and/or emergency craniotomy or burr hole exploration. Any changes in the condition, especially changes in breathing and ventricular pressure, should be treated with controlled breathing, tracheal cleaning and artificial hyperventilation. If it still cannot be corrected quickly, measure the arterial carbon dioxide partial pressure and arterial oxygen partial pressure. In order to minimize decerebrate tonic attacks, pethidine and chlorpromazine can be given as needed, and sometimes diazepam is added. If it is ineffective, and the ventricular pressure increases to 40 mmHg or higher, the following methods can be adopted in sequence: (1) clear the secretions in the trachea, and then perform artificial hyperventilation for 5 minutes