New progress in drug treatment of Parkinson's disease (Xu) Clinical application of levodopa and its enhancers (Literature review)

Abstract

Although the levodopa enhancer levodopa is more effective than other drugs for treating Parkinson's syndrome, its efficacy is limited because some patients cannot tolerate its side effects. Sometimes, although a fixed dose is applied to the same patient, the clinical response may fluctuate every day or even hours, making it difficult for doctors to control the drug. For this reason, research on levodopa enhancers has been carried out recently, and it has been initially found that the following types of drugs have synergistic effects with levodopa, which can enhance levodopa