Activator analysis of curative effect of endovascular treatment for left intracranial vein thrombosis

Abstract

Purpose This study aims to evaluate the clinical effects and patient benefits of endovascular treatment and traditional anticoagulation in the treatment of intracranial venous sinus thrombosis (CVST), provide a reference for clinical work, and achieve the purpose of standardizing diagnosis and treatment. Methods: CVST patients admitted to this hospital from January 2017 to September 2020 were retrospectively collected, and telephone follow-ups were conducted from 3 months to 46 months after discharge. Finally, 115 CVST patients were included, 75 of whom were on anticoagulant therapy. Basically, they received endovascular treatment, and the other 40 cases only received simple anticoagulation therapy. Analyze the clinical treatment effects and patient benefits of different treatment methods. Results Both groups of treatments could significantly improve the prognosis of patients, and the difference was statistically significant (P<0.001). More patients (96.0%) who received endovascular treatment had a good prognosis (m RS = 0 to 2 points) than those who received anticoagulant therapy alone (87.5%), but the difference was not statistically significant (P>0.05); Compared with patients who fully recovered from anticoagulation therapy (78.7%) (78.7%) and those who fully recovered from anticoagulation therapy (77.5%), the difference was not statistically significant (P>0.05). Statistically significant indicators in general clinical data and factors that have been proven to affect prognosis were adjusted as covariates. Different treatment methods were not found to be associated with good prognosis (m RS = 0 to 2 points), complete recovery (m RS =0), all P>0.05. The median hospitalization cost for endovascular treatment was 44 616.83 yuan, and the median hospitalization cost for anticoagulation therapy alone was 19 328.02 yuan. The difference was statistically significant (P<0.001). The median hospitalization time for endovascular combined therapy was 16 days, and the median hospitalization time for anticoagulation therapy was 15 days, with no statistically significant difference (P>0.05). Conclusion Both endovascular therapy and anticoagulation therapy can significantly improve the prognosis of patients, but the difference between the two is not statistically significant. Endovascular treatment has higher hospitalization costs than anticoagulation alone. Endovascular therapy did not reduce hospital stay compared with anticoagulant therapy alone. [International Journal of Neurology Neurosurgery, 2021, 48(6):516-520.]