Collection And Screening Of Medicinal Plants To Access Its Tyrosinase Inhibition Activity Using HPTLC And GC-MS For Skin Melanogenesis

Abstract

Tyrosinase is a key amino acid that catalyzes the synthesis of melanin in plants, microbes, and pigment cells, also known as polyphenol oxidase. The intracellular compound of melanin biosynthesis is helpful for skin lightening agents used in products and for hyperpigmentation disorders. Going to contribute to their role in cancer prevention tissue remodelling. Tyrosinase enzyme has been used as a model organism for assessing plant extract's anti-tyrosinase behaviour. The objective of this work was to examine the inhibitory behaviour of 57 plants using methods of cell death of mushroom tyrosinase. In the very same solvent structures, plant extracts have been prepared in hexane, ethyl acetate, methanol, ethanol, isopropanol, and water-positive kojic acid regulates. Five plants were tested among the screened herbal plants, higher oxidative stress was found in Glycyrrhiza glabra and Mutingia calabura