Fresh Views on Stroke Management: Time-Honored Problems and Novel Approaches

Abstract

Stroke is a major global cause of disability and mortality, and it carries a heavy social cost in terms of disability, mortality, and medical expenses. Recently, there has been a resurgence of interest in disease-modifying treatments and innovative techniques in the acute stroke situation, which has improved patient outcomes and decreased long-term disability. The tenet that "time is brain" has been disproved in recent years, and improved outcomes have resulted from the application of cutting-edge neuroimaging techniques in acute clinical practice. These techniques enable the administration of acute treatments to patients who were previously ineligible based solely on temporal selection. New research on thrombectomy has made it possible to choose stroke patients up to 24 hours after symptoms start by employing sophisticated neuroradiological techniques like magnetic resonance imaging (MRI) and computer tomography perfusion (CTP). Significant therapeutic advancements have also been made possible by the use of newer oral anticoagulants (NOACs) for atrial fibrillation and more efficient acute care of stroke patients in specialized wards (stroke units). We emphasize recent advancements in the diagnosis, treatment, and prevention of acute and chronic stroke problems. In this editorial paper, we synthesize the current knowledge about the major stroke-related breakthroughs and perspectives and their relevance in stroke care. We then go over a few studies that were included in the "Clinical Research on Ischemic Stroke: Novel Approaches in Acute and Chronic Phase" Special Issue.