Experimental study on death and complications caused by Ian's convulsions
Keywords:
electric convulsions; rats; experimental research; animal experiments; atropine; control group; lactic acidosis; sodium bicarbonate solution; complications; arrhythmiaAbstract
The author used 28 hybrid cats and 198 white rats to conduct animal experiments. With over-limit electric convulsions [alternating current, 170 volts (cat) and 150 volts (rat), one second], resulting in status epilepticus similar to humans. Fifteen atropinized tomcats were given electric convulsions every 30 seconds until they died, or the total number of electric convulsions reached 200. Those animals that did not die from cardiac arrhythmia in the early stage of the experiment were divided into 3 groups. The three cats in the first group received no other treatment except atropine (all animals had been given this drug), and the three cats in the second group received Intravenous injection with isotonic sodium bicarbonate solution, the dosage is sufficient to correct acidosis. Two other cats were given intravenous bicarbonate, but not enough to prevent severe acidosis. Three cats in group 3 were given isotonic saline to make their blood