Central nervous system endothelial hyperplasia, a treatable multiple choking dementia

Abstract

Neoplastic vascular endothelial hyperplasia is a rare vascular disease; it is characterized by a series of strange neurological symptoms such as dementia, stroke-like attacks and skin lesions. There is extensive proliferation of vascular endothelial cells in blood vessels throughout the body. It is also called "systemic proliferative vascular endothelial hypertrophy" and "diffuse malignant vascular endothelial hyperplasia" in the literature. This article reports one such case that had a marked response to steroid therapy for neurologic symptoms. Case Report A 59-year-old woman, right-handed, was admitted to hospital with progressive dementia and left hemiparesis. Two months ago, she had a sudden onset of aphasia and weakness of the right side of her body. A week later, due to multiple episodes of incoherent speech, a brain scan was performed at the local hospital